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The HPE ProLiant DL380 Gen10 26×2.5″ Server is a secure, high-density, and versatile enterprise server engineered to deliver superior performance and scalability. Built on Hewlett Packard Enterprise’s most trusted platform, it combines Intel® Xeon® Scalable processors, HPE DDR4 SmartMemory, and Intel Optane™ persistent memory to meet the demands of modern data-intensive workloads with confidence and reliability.
With its 26×2.5″ SFF bays, the HPE DL380 Gen10 provides outstanding storage density, supporting SSDs, HDDs, and NVMe drives in a flexible 2U chassis. This makes it an ideal solution for virtualization, high-performance databases, AI, and mission-critical enterprise applications.
The HPE ProLiant DL380 Gen10 26×2.5″ Server stands out as a future-proof, enterprise-class platform that blends compute power, storage versatility, and advanced management for evolving IT needs.
HPE Trusted Supply Chain safeguards against counterfeit components and malicious microcode.
Servers are manufactured in secure HPE facilities with rigorous end-to-end inspections.
Ensures full lifecycle protection for sensitive data and applications.
Powered by 1 or 2 Intel® Xeon® Scalable processors with up to 28 cores each.
Up to 60% performance gains and 27% more cores compared to prior generations.
Supports up to 3.0 TB HPE DDR4 SmartMemory, or 6.0 TB with Intel Optane™ persistent memory.
Supports up to 7x NVIDIA Tesla T4 GPUs or Xilinx Alveo accelerators.
Optimized for AI inferencing, HPC, rendering, VDI, and deep learning.
The DL380 Gen10 26×2.5″ Server delivers massive storage scalability and high compute performance, making it suitable for both traditional and emerging workloads.
Up to 56 cores in a dual-socket configuration.
Wide support for Intel Xeon families (8100/8200, 6100/6200, 5100/5200, etc.).
Processor speeds up to 3.9 GHz with cache sizes between 8.25 MB – 38.5 MB.
24 DIMM slots with DDR4 SmartMemory.
Intel Optane Persistent Memory Series 100 support for hybrid and in-memory workloads.
Unlocks faster analytics, in-memory database acceleration, and real-time application insights.
The HPE ProLiant DL380 Gen10 26×2.5″ Server chassis is built for enterprises that demand maximum storage capacity without sacrificing performance.
Supports up to 26 SFF SAS/SATA/SSD drives.
Optional rear expansion for 2–6 additional SFF drives or 2 Dual UFF drives.
Up to 20 NVMe drives for latency-sensitive workloads.
Integrated HPE Smart Array Controllers with RAID and HBA modes.
Dual M.2 SATA SSDs for secure and redundant OS boot.
This design is ideal for:
High-performance databases with SSD/NVMe.
Large virtualization and VDI clusters.
Data-intensive hybrid workloads needing both SSD performance and HDD capacity.
Embedded 4x1GbE LOM included.
Networking Choice (NC) models for customizable NIC configurations.
HPE FlexibleLOM adapters ranging from 1GbE to 100GbE.
Up to 8 PCIe expansion slots for GPUs, advanced NICs, and storage controllers.
HPE iLO 5 provides intelligent health monitoring and remote server management.
Security features include:
Server Configuration Lock
iLO Security Dashboard
Workload Performance Advisor
HPE OneView delivers centralized IT infrastructure management.
HPE InfoSight adds AI-driven predictive analytics and proactive support.
Optional TPM 2.0 module and chassis intrusion detection for enhanced hardware-level protection.
Microsoft Windows Server 2016, 2019, 2022
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
Ubuntu Server
Oracle Linux / Oracle VM
Citrix XenServer
Container and cloud-native platforms like Docker and Azure Stack HCI
The HPE ProLiant DL380 Gen10 26×2.5″ Server is best suited for:
Large-scale databases and in-memory analytics.
High-density virtualization and VDI environments.
AI, ML, and HPC workloads requiring ultra-fast storage.
Enterprise-critical workloads (ERP, CRM, financial applications).
Private cloud, hybrid cloud, and data center consolidation.
Ultra-dense 26-bay SFF chassis for maximum storage capacity and flexibility.
Enterprise-class reliability with HPE Trusted Supply Chain.
Scalable compute with Intel Xeon Scalable processors.
Flexible networking support up to 100GbE.
GPU-ready design for HPC, AI, and advanced analytics workloads.
The HPE ProLiant DL380 Gen10 26×2.5″ Server combines ultra-high storage density with enterprise-class compute and security in a 2U rack design. With its 26×2.5″ SFF bays, organizations can build the perfect mix of HDD, SSD, and NVMe drives to support any workload requirement.
Backed by Intel Xeon Scalable processors, HPE SmartMemory, and Intel Optane Persistent Memory, it provides the performance and scalability needed for the most demanding enterprise and cloud-native applications. The HPE ProLiant DL380 Gen10 26×2.5″ Server is a forward-looking investment that scales seamlessly with business growth.
| Form factor | 2U |
|---|---|
| Processor | Intel® Xeon® Scalable processors. |
| No. of processor socket | 2 |
| Ram type | DDR4 |
| Total Memory slots | 24 DIMM slots |
| Max memory | Up to 3 TB DDR4 2933 MT/s |
| PCIe slots | 8 PCIe 3.0 slots |
| Support hard drive | 24 SFF bay with additional 6SFF rear drive bay option to total 30 SFF drives |
| Support raid controller | -Software RAID HPE Smart Array S100i SR Gen10 SW RAID Essential RAID Controller HPE Smart Array E208i-a SR Gen10 Controller HPE Smart Array E208i-p SR Gen10 Controller HPE Smart Array E208e-p SR Gen10 Controller -Performance RAID Controller Broadcom MegaRAID MR416i-a Controller for HPE Broadcom MegaRAID MR416i-p Controller for HPE Broadcom MegaRAID MR216i-a Controller for HPE Broadcom MegaRAID MR216i-p Controller for HPE HPE Smart Array P408i-a SR Gen10 Controller HPE Smart Array P408i-p SR Gen10 Controller HPE Smart Array P408e-p SR Gen10 Controller HPE Smart Array P816i-a SR Gen10 Controlle |
| Network controller | 1x Embedded 4 x 1GbE Network Adapter |
| I/O Port | -Serial : Optional, rear -Display port : 1 (SFF 1 front, optional via Universal Media Bay), 8 LFF chassis standard -Network ports : 4 x 1GbE embedded (if equipped/depending on model) One (1) FlexibleLOM slot available on all chassis types (supporting various NIC adapters) -Micro SD Slot : 1 Micro SD -USB 3.0 : Up to 5 total: 1 front, 2 rear, 2 internal (secure), 2 optional USB 2.0 front via Universal Media Bay, or standard on 8LFF chassis |
| Power supply | 500W , 800W , 1600W Platinum |
| Remote management | HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE iLO Advanced Premium Security Edition and HPE OneView Advanced (require licenses) |
| Operating system | Windows Server Micrsoft Hyper-V Server VMware vSphere ClearOS Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) Ubuntu Oracle Linux Citrix |
| Dimensions | 8.73 x 44.54 x 67.94 cm / 3.44 x 17.54 x 26.75 in |
| Weight | Max : 19.5 kg / 43.00 lbs. Min : 14.9 kg / 32.75 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
Only logged in customers who have purchased this product may leave a review.
The HPE ProLiant DL380 Gen10 26×2.5″ Server is a secure, high-density, and versatile enterprise server engineered to deliver superior performance and scalability. Built on Hewlett Packard Enterprise’s most trusted platform, it combines Intel® Xeon® Scalable processors, HPE DDR4 SmartMemory, and Intel Optane™ persistent memory to meet the demands of modern data-intensive workloads with confidence and reliability.
With its 26×2.5″ SFF bays, the HPE DL380 Gen10 provides outstanding storage density, supporting SSDs, HDDs, and NVMe drives in a flexible 2U chassis. This makes it an ideal solution for virtualization, high-performance databases, AI, and mission-critical enterprise applications.
The HPE ProLiant DL380 Gen10 26×2.5″ Server stands out as a future-proof, enterprise-class platform that blends compute power, storage versatility, and advanced management for evolving IT needs.
HPE Trusted Supply Chain safeguards against counterfeit components and malicious microcode.
Servers are manufactured in secure HPE facilities with rigorous end-to-end inspections.
Ensures full lifecycle protection for sensitive data and applications.
Powered by 1 or 2 Intel® Xeon® Scalable processors with up to 28 cores each.
Up to 60% performance gains and 27% more cores compared to prior generations.
Supports up to 3.0 TB HPE DDR4 SmartMemory, or 6.0 TB with Intel Optane™ persistent memory.
Supports up to 7x NVIDIA Tesla T4 GPUs or Xilinx Alveo accelerators.
Optimized for AI inferencing, HPC, rendering, VDI, and deep learning.
The DL380 Gen10 26×2.5″ Server delivers massive storage scalability and high compute performance, making it suitable for both traditional and emerging workloads.
Up to 56 cores in a dual-socket configuration.
Wide support for Intel Xeon families (8100/8200, 6100/6200, 5100/5200, etc.).
Processor speeds up to 3.9 GHz with cache sizes between 8.25 MB – 38.5 MB.
24 DIMM slots with DDR4 SmartMemory.
Intel Optane Persistent Memory Series 100 support for hybrid and in-memory workloads.
Unlocks faster analytics, in-memory database acceleration, and real-time application insights.
The HPE ProLiant DL380 Gen10 26×2.5″ Server chassis is built for enterprises that demand maximum storage capacity without sacrificing performance.
Supports up to 26 SFF SAS/SATA/SSD drives.
Optional rear expansion for 2–6 additional SFF drives or 2 Dual UFF drives.
Up to 20 NVMe drives for latency-sensitive workloads.
Integrated HPE Smart Array Controllers with RAID and HBA modes.
Dual M.2 SATA SSDs for secure and redundant OS boot.
This design is ideal for:
High-performance databases with SSD/NVMe.
Large virtualization and VDI clusters.
Data-intensive hybrid workloads needing both SSD performance and HDD capacity.
Embedded 4x1GbE LOM included.
Networking Choice (NC) models for customizable NIC configurations.
HPE FlexibleLOM adapters ranging from 1GbE to 100GbE.
Up to 8 PCIe expansion slots for GPUs, advanced NICs, and storage controllers.
HPE iLO 5 provides intelligent health monitoring and remote server management.
Security features include:
Server Configuration Lock
iLO Security Dashboard
Workload Performance Advisor
HPE OneView delivers centralized IT infrastructure management.
HPE InfoSight adds AI-driven predictive analytics and proactive support.
Optional TPM 2.0 module and chassis intrusion detection for enhanced hardware-level protection.
Microsoft Windows Server 2016, 2019, 2022
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
Ubuntu Server
Oracle Linux / Oracle VM
Citrix XenServer
Container and cloud-native platforms like Docker and Azure Stack HCI
The HPE ProLiant DL380 Gen10 26×2.5″ Server is best suited for:
Large-scale databases and in-memory analytics.
High-density virtualization and VDI environments.
AI, ML, and HPC workloads requiring ultra-fast storage.
Enterprise-critical workloads (ERP, CRM, financial applications).
Private cloud, hybrid cloud, and data center consolidation.
Ultra-dense 26-bay SFF chassis for maximum storage capacity and flexibility.
Enterprise-class reliability with HPE Trusted Supply Chain.
Scalable compute with Intel Xeon Scalable processors.
Flexible networking support up to 100GbE.
GPU-ready design for HPC, AI, and advanced analytics workloads.
The HPE ProLiant DL380 Gen10 26×2.5″ Server combines ultra-high storage density with enterprise-class compute and security in a 2U rack design. With its 26×2.5″ SFF bays, organizations can build the perfect mix of HDD, SSD, and NVMe drives to support any workload requirement.
Backed by Intel Xeon Scalable processors, HPE SmartMemory, and Intel Optane Persistent Memory, it provides the performance and scalability needed for the most demanding enterprise and cloud-native applications. The HPE ProLiant DL380 Gen10 26×2.5″ Server is a forward-looking investment that scales seamlessly with business growth.
| Form factor | 2U |
|---|---|
| Processor | Intel® Xeon® Scalable processors. |
| No. of processor socket | 2 |
| Ram type | DDR4 |
| Total Memory slots | 24 DIMM slots |
| Max memory | Up to 3 TB DDR4 2933 MT/s |
| PCIe slots | 8 PCIe 3.0 slots |
| Support hard drive | 24 SFF bay with additional 6SFF rear drive bay option to total 30 SFF drives |
| Support raid controller | -Software RAID HPE Smart Array S100i SR Gen10 SW RAID Essential RAID Controller HPE Smart Array E208i-a SR Gen10 Controller HPE Smart Array E208i-p SR Gen10 Controller HPE Smart Array E208e-p SR Gen10 Controller -Performance RAID Controller Broadcom MegaRAID MR416i-a Controller for HPE Broadcom MegaRAID MR416i-p Controller for HPE Broadcom MegaRAID MR216i-a Controller for HPE Broadcom MegaRAID MR216i-p Controller for HPE HPE Smart Array P408i-a SR Gen10 Controller HPE Smart Array P408i-p SR Gen10 Controller HPE Smart Array P408e-p SR Gen10 Controller HPE Smart Array P816i-a SR Gen10 Controlle |
| Network controller | 1x Embedded 4 x 1GbE Network Adapter |
| I/O Port | -Serial : Optional, rear -Display port : 1 (SFF 1 front, optional via Universal Media Bay), 8 LFF chassis standard -Network ports : 4 x 1GbE embedded (if equipped/depending on model) One (1) FlexibleLOM slot available on all chassis types (supporting various NIC adapters) -Micro SD Slot : 1 Micro SD -USB 3.0 : Up to 5 total: 1 front, 2 rear, 2 internal (secure), 2 optional USB 2.0 front via Universal Media Bay, or standard on 8LFF chassis |
| Power supply | 500W , 800W , 1600W Platinum |
| Remote management | HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE iLO Advanced Premium Security Edition and HPE OneView Advanced (require licenses) |
| Operating system | Windows Server Micrsoft Hyper-V Server VMware vSphere ClearOS Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) Ubuntu Oracle Linux Citrix |
| Dimensions | 8.73 x 44.54 x 67.94 cm / 3.44 x 17.54 x 26.75 in |
| Weight | Max : 19.5 kg / 43.00 lbs. Min : 14.9 kg / 32.75 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
The HPE ProLiant DL380 Gen10 26×2.5″ Server is a secure, high-density, and versatile enterprise server engineered to deliver superior performance and scalability. Built on Hewlett Packard Enterprise’s most trusted platform, it combines Intel® Xeon® Scalable processors, HPE DDR4 SmartMemory, and Intel Optane™ persistent memory to meet the demands of modern data-intensive workloads with confidence and reliability.
With its 26×2.5″ SFF bays, the HPE DL380 Gen10 provides outstanding storage density, supporting SSDs, HDDs, and NVMe drives in a flexible 2U chassis. This makes it an ideal solution for virtualization, high-performance databases, AI, and mission-critical enterprise applications.
The HPE ProLiant DL380 Gen10 26×2.5″ Server stands out as a future-proof, enterprise-class platform that blends compute power, storage versatility, and advanced management for evolving IT needs.
HPE Trusted Supply Chain safeguards against counterfeit components and malicious microcode.
Servers are manufactured in secure HPE facilities with rigorous end-to-end inspections.
Ensures full lifecycle protection for sensitive data and applications.
Powered by 1 or 2 Intel® Xeon® Scalable processors with up to 28 cores each.
Up to 60% performance gains and 27% more cores compared to prior generations.
Supports up to 3.0 TB HPE DDR4 SmartMemory, or 6.0 TB with Intel Optane™ persistent memory.
Supports up to 7x NVIDIA Tesla T4 GPUs or Xilinx Alveo accelerators.
Optimized for AI inferencing, HPC, rendering, VDI, and deep learning.
The DL380 Gen10 26×2.5″ Server delivers massive storage scalability and high compute performance, making it suitable for both traditional and emerging workloads.
Up to 56 cores in a dual-socket configuration.
Wide support for Intel Xeon families (8100/8200, 6100/6200, 5100/5200, etc.).
Processor speeds up to 3.9 GHz with cache sizes between 8.25 MB – 38.5 MB.
24 DIMM slots with DDR4 SmartMemory.
Intel Optane Persistent Memory Series 100 support for hybrid and in-memory workloads.
Unlocks faster analytics, in-memory database acceleration, and real-time application insights.
The HPE ProLiant DL380 Gen10 26×2.5″ Server chassis is built for enterprises that demand maximum storage capacity without sacrificing performance.
Supports up to 26 SFF SAS/SATA/SSD drives.
Optional rear expansion for 2–6 additional SFF drives or 2 Dual UFF drives.
Up to 20 NVMe drives for latency-sensitive workloads.
Integrated HPE Smart Array Controllers with RAID and HBA modes.
Dual M.2 SATA SSDs for secure and redundant OS boot.
This design is ideal for:
High-performance databases with SSD/NVMe.
Large virtualization and VDI clusters.
Data-intensive hybrid workloads needing both SSD performance and HDD capacity.
Embedded 4x1GbE LOM included.
Networking Choice (NC) models for customizable NIC configurations.
HPE FlexibleLOM adapters ranging from 1GbE to 100GbE.
Up to 8 PCIe expansion slots for GPUs, advanced NICs, and storage controllers.
HPE iLO 5 provides intelligent health monitoring and remote server management.
Security features include:
Server Configuration Lock
iLO Security Dashboard
Workload Performance Advisor
HPE OneView delivers centralized IT infrastructure management.
HPE InfoSight adds AI-driven predictive analytics and proactive support.
Optional TPM 2.0 module and chassis intrusion detection for enhanced hardware-level protection.
Microsoft Windows Server 2016, 2019, 2022
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
Ubuntu Server
Oracle Linux / Oracle VM
Citrix XenServer
Container and cloud-native platforms like Docker and Azure Stack HCI
The HPE ProLiant DL380 Gen10 26×2.5″ Server is best suited for:
Large-scale databases and in-memory analytics.
High-density virtualization and VDI environments.
AI, ML, and HPC workloads requiring ultra-fast storage.
Enterprise-critical workloads (ERP, CRM, financial applications).
Private cloud, hybrid cloud, and data center consolidation.
Ultra-dense 26-bay SFF chassis for maximum storage capacity and flexibility.
Enterprise-class reliability with HPE Trusted Supply Chain.
Scalable compute with Intel Xeon Scalable processors.
Flexible networking support up to 100GbE.
GPU-ready design for HPC, AI, and advanced analytics workloads.
The HPE ProLiant DL380 Gen10 26×2.5″ Server combines ultra-high storage density with enterprise-class compute and security in a 2U rack design. With its 26×2.5″ SFF bays, organizations can build the perfect mix of HDD, SSD, and NVMe drives to support any workload requirement.
Backed by Intel Xeon Scalable processors, HPE SmartMemory, and Intel Optane Persistent Memory, it provides the performance and scalability needed for the most demanding enterprise and cloud-native applications. The HPE ProLiant DL380 Gen10 26×2.5″ Server is a forward-looking investment that scales seamlessly with business growth.
| Form factor | 2U |
|---|---|
| Processor | Intel® Xeon® Scalable processors. |
| No. of processor socket | 2 |
| Ram type | DDR4 |
| Total Memory slots | 24 DIMM slots |
| Max memory | Up to 3 TB DDR4 2933 MT/s |
| PCIe slots | 8 PCIe 3.0 slots |
| Support hard drive | 24 SFF bay with additional 6SFF rear drive bay option to total 30 SFF drives |
| Support raid controller | -Software RAID HPE Smart Array S100i SR Gen10 SW RAID Essential RAID Controller HPE Smart Array E208i-a SR Gen10 Controller HPE Smart Array E208i-p SR Gen10 Controller HPE Smart Array E208e-p SR Gen10 Controller -Performance RAID Controller Broadcom MegaRAID MR416i-a Controller for HPE Broadcom MegaRAID MR416i-p Controller for HPE Broadcom MegaRAID MR216i-a Controller for HPE Broadcom MegaRAID MR216i-p Controller for HPE HPE Smart Array P408i-a SR Gen10 Controller HPE Smart Array P408i-p SR Gen10 Controller HPE Smart Array P408e-p SR Gen10 Controller HPE Smart Array P816i-a SR Gen10 Controlle |
| Network controller | 1x Embedded 4 x 1GbE Network Adapter |
| I/O Port | -Serial : Optional, rear -Display port : 1 (SFF 1 front, optional via Universal Media Bay), 8 LFF chassis standard -Network ports : 4 x 1GbE embedded (if equipped/depending on model) One (1) FlexibleLOM slot available on all chassis types (supporting various NIC adapters) -Micro SD Slot : 1 Micro SD -USB 3.0 : Up to 5 total: 1 front, 2 rear, 2 internal (secure), 2 optional USB 2.0 front via Universal Media Bay, or standard on 8LFF chassis |
| Power supply | 500W , 800W , 1600W Platinum |
| Remote management | HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE iLO Advanced Premium Security Edition and HPE OneView Advanced (require licenses) |
| Operating system | Windows Server Micrsoft Hyper-V Server VMware vSphere ClearOS Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) Ubuntu Oracle Linux Citrix |
| Dimensions | 8.73 x 44.54 x 67.94 cm / 3.44 x 17.54 x 26.75 in |
| Weight | Max : 19.5 kg / 43.00 lbs. Min : 14.9 kg / 32.75 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
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