Description

HPE ProLiant DL380 Gen10 24×2.5″ Server – High-Density, Scalable, and Enterprise-Grade

The HPE ProLiant DL380 Gen10 24×2.5″ Server is a powerful, secure, and flexible enterprise server designed to maximize storage density and performance. Built on Hewlett Packard Enterprise’s most trusted platform, it combines Intel® Xeon® Scalable processors, HPE DDR4 SmartMemory, and Intel Optane™ persistent memory to deliver exceptional scalability, security, and reliability for modern IT workloads.

With its 24×2.5″ SFF bays, the HPE ProLiant DL380 Gen10 24×2.5″ Server offers unmatched storage flexibility—supporting performance-focused SSDs, high-capacity HDDs, and NVMe drives to meet the demands of enterprise applications. This high-density 2U server is ideal for virtualization, AI, databases, and mission-critical business workloads.

The HPE ProLiant DL380 Gen10 24×2.5″ Server stands out as a versatile, enterprise-class solution that balances compute, storage, and networking for future-ready IT environments.

Key Features

Defend Applications and Data Before Your Server is Built

• HPE Trusted Supply Chain ensures protection against counterfeit components and malicious microcode.

• Manufactured in secure HPE facilities with rigorous inspections.

• Provides lifecycle-long protection for sensitive data and workloads.

World-Class Performance

• Powered by 1 or 2 Intel® Xeon® Scalable processors with up to 28 cores each.

• Up to 60% performance gains and 27% more cores compared to previous generations.

• Supports HPE DDR4 SmartMemory up to 3.0 TB, or 6.0 TB with Intel Optane™ persistent memory.

Enhanced GPU Density

• Supports up to 7x NVIDIA Tesla T4 GPUs or Xilinx Alveo accelerators.

• Optimized for AI inferencing, VDI, rendering, HPC, and deep learning.

Performance and Scalability

The DL380 Gen10 24×2.5″ offers greater storage scalability while maintaining high compute performance.

Processor Architecture

• Up to 56 cores in a dual-socket configuration.

• Supports multiple Intel Xeon processor families (8100/8200, 6100/6200, 5100/5200, etc.).

• Speeds up to 3.9 GHz with cache sizes ranging from 8.25 MB to 38.5 MB.

Memory Flexibility

• 24 DIMM slots with DDR4 SmartMemory.

• Intel Optane Persistent Memory Series 100 support for hybrid workloads.

• Accelerates analytics, in-memory databases, and real-time applications.

Storage and Expansion

The HPE ProLiant DL380 Gen10 24×2.5″ Server chassis provides enterprises with high-density storage for performance-hungry workloads.

• Supports up to 24 SFF SAS/SATA/SSD drives.

• Optional rear expansion for up to 6 additional SFF drives or 2 Dual UFF drives.

• Up to 20 NVMe drives for ultra-low-latency applications.

• Integrated HPE Smart Array Controllers (RAID and HBA modes).

• Dual M.2 SATA SSDs for redundant OS boot.

Ideal for:

• Database acceleration with SSD/NVMe.

• Large virtualization clusters.

• High-capacity hybrid workloads requiring both HDD and SSD.

Networking and Connectivity

• Embedded 4x1GbE LOM standard.

• Networking Choice (NC) models for flexible NIC selection.

• HPE FlexibleLOM adapters from 1GbE up to 100GbE.

• Up to 8 PCIe expansion slots for GPUs, NICs, and storage controllers.

Management and Security

• HPE iLO 5 for intelligent monitoring and server health management.

• Security features:

  • Server Configuration Lock

  • iLO Security Dashboard

  • Workload Performance Advisor

• HPE OneView for centralized infrastructure management.

• HPE InfoSight AI-driven predictive analytics.

• Optional TPM 2.0 and chassis intrusion detection.

Operating System Support

• Microsoft Windows Server 2016, 2019, 2022

• VMware vSphere / ESXi

• Red Hat Enterprise Linux (RHEL)

• SUSE Linux Enterprise Server (SLES)

• Ubuntu Server

• Oracle Linux / Oracle VM

• Citrix XenServer

• Container and cloud-native platforms like Docker and Azure Stack HCI

Use Cases

The HPE ProLiant DL380 Gen10 24×2.5″ Server is ideal for:

• Large databases and in-memory workloads.

• High-performance virtualization and VDI environments.

• AI, ML, and HPC applications requiring fast I/O.

• Business-critical enterprise applications (ERP, CRM).

• Data center consolidation and private cloud deployments.

Why Choose HPE ProLiant DL380 Gen10 24×2.5″ Server?

• High-density 24-bay SFF chassis for maximum storage scalability.

• Enterprise-class reliability with HPE Trusted Supply Chain.

• Scalable compute power with Intel Xeon Scalable processors.

• Flexible networking up to 100GbE.

• GPU-ready for AI, HPC, and deep learning workloads.

Conclusion

The HPE ProLiant DL380 Gen10 24×2.5″ Server delivers an unbeatable balance of compute, storage, and scalability in a dense 2U form factor. With its 24×2.5″ SFF storage bays, enterprises can configure the perfect mix of SSDs, HDDs, and NVMe drives to match workload demands.

Backed by Intel Xeon Scalable processors, HPE SmartMemory, and Intel Optane Persistent Memory, this server ensures industry-leading performance across databases, AI, virtualization, and enterprise applications. It is a future-proof investment designed to grow with your business.

Check full specs and datasheet below: Spec sheet