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The HPE ProLiant DL380 Gen11 8×2.5″ Server is a next-generation, dual-socket rack server built for high-performance computing, hybrid cloud workloads, and data-intensive enterprise applications. Designed to deliver exceptional scalability and speed, it is powered by 4th and 5th Gen Intel® Xeon® Scalable Processors, supporting up to 64 cores per CPU and 8 TB DDR5 memory.
With its advanced PCIe Gen5 architecture, enhanced bandwidth, and integrated security at the silicon level, the HPE ProLiant DL380 Gen11 8×2.5″ Server is the ideal choice for organizations running mission-critical workloads, virtualization, or AI-driven applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server sets a new standard for compute performance. It supports up to two Intel Xeon Scalable processors, offering up to 64 cores per processor and 350W TDP for maximum throughput.
This server includes DDR5 Smart Memory at speeds up to 5600 MHz, delivering higher bandwidth, lower latency, and increased energy efficiency compared to DDR4. With 16 DIMM channels per processor and up to 8 TB total memory, businesses benefit from unmatched parallel processing for workloads such as virtualization, AI, ML, and data analytics.
Additionally, the support for PCIe Gen5 technology provides up to double the data transfer rate of Gen4, ensuring faster networking and higher I/O bandwidth for intensive applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server offers outstanding storage flexibility with support for multiple drive configurations. It can accommodate 8x 2.5″ SAS, SATA, or NVMe SSDs, depending on model and workload requirements.
The server’s architecture also supports hot-pluggable RAID M.2 boot options, and a range of HPE Smart Array Controllers (such as SR932i-p, MR216i-o, and MR416i-p) to ensure optimal performance, reliability, and data protection.
For businesses requiring expansion, the HPE ProLiant DL380 Gen11 8×2.5″ Server includes up to 8 PCIe Gen5 slots and 2 OCP 3.0 slots, enabling future scalability with network adapters, GPUs, or high-speed storage controllers.
Designed for high-speed communication and data throughput, the HPE ProLiant DL380 Gen11 8×2.5″ Server supports flexible networking options, including 1GbE, 10GbE, 25GbE, 100GbE, and even 200GbE adapters in PCIe or OCP 3.0 form factors.
This makes it an excellent fit for organizations that require ultra-low-latency networking, hybrid cloud environments, or large-scale data center integration. The inclusion of PCIe Gen5 lanes also enhances overall network speed and reduces bottlenecks, ensuring smoother and faster data transmission across workloads.
Security is at the heart of the HPE ProLiant DL380 Gen11 8×2.5″ Server, which integrates HPE Silicon Root of Trust—a hardware-based zero-trust architecture that ensures all firmware is authenticated before booting.
The server also leverages Intel® Software Guard Extensions (SGX) and Intel® Boot Guard, providing hardware-level protection for sensitive data and applications.
With features like TPM 2.0, intrusion detection, and secure firmware validation, the HPE ProLiant DL380 Gen11 8×2.5″ Server delivers multi-layered defense to safeguard business data from cyber threats and unauthorized access.
The HPE ProLiant DL380 Gen11 8×2.5″ Server includes HPE Integrated Lights-Out 6 (iLO 6) for advanced, secure, and remote management capabilities. IT administrators can configure, monitor, and update servers seamlessly, even from offsite locations.
For a complete cloud-based experience, HPE Compute Ops Management enables global visibility, automation, and lifecycle control of compute resources from edge to cloud.
Additionally, the server integrates with HPE OneView and HPE GreenLake, providing a unified, as-a-service management approach for hybrid infrastructure, improving operational efficiency and reducing downtime.
The HPE ProLiant DL380 Gen11 8×2.5″ Server is engineered to handle a variety of demanding workloads, including:
Virtualization and containerized environments
AI and machine learning model training
Database analytics and business intelligence
Software-defined storage (SDS)
Media processing and video transcoding
Edge and hybrid cloud infrastructure
Its scalability and performance make it a trusted platform for enterprises seeking consistent power, flexibility, and resilience in their IT environments.
The HPE ProLiant DL380 Gen11 8×2.5″ Server supports a wide array of operating systems and hypervisors, including:
Microsoft Windows Server
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
CentOS and Oracle Linux
Ubuntu Server
This broad compatibility ensures seamless integration into any enterprise ecosystem or hybrid cloud infrastructure.
Choosing the HPE ProLiant DL380 Gen11 8×2.5″ Server means choosing a future-proof solution built for performance, reliability, and scalability. It combines next-generation Intel Xeon Scalable processors, DDR5 memory, and PCIe Gen5 technology to deliver industry-leading efficiency.
With HPE’s Silicon Root of Trust, iLO 6, and Compute Ops Management, organizations benefit from enhanced automation, zero-trust security, and simplified IT operations—making it ideal for any modern data center or enterprise deployment.
In conclusion, the HPE ProLiant DL380 Gen11 8×2.5″ Server stands out as one of the most powerful and secure servers in its class. It offers advanced compute capabilities, flexible storage options, and enterprise-grade security designed for the hybrid cloud era.
Whether used for AI workloads, virtualization, or mission-critical business applications, the HPE ProLiant DL380 Gen11 8×2.5″ Server ensures exceptional reliability, intelligent management, and scalable performance—empowering organizations to meet evolving IT demands with confidence.
| Form factor | 2U |
|---|---|
| Processor | 5th Gen Intel® Xeon® Scalable Processors and 4th Gen Intel® Xeon® Scalable Processors |
| Ram type | DDR5 |
| Total Memory slots | 32 DIMM Slots |
| Max memory | 8.0 TB 32 x 256 GB RDIMM @ 4800 MT/s |
| PCIe slots | Up to 8 PCIe Gen5, and 2 OCP 3.0 |
| Support hard drive | 8 SFF SAS/SATA/SSD |
| Support raid controller | HPE SR932i-p and/or HPE MR216i-o and/or HPE MR416i-o and/or HPE MR216i-p and/or HPE MR416i-p and/or HPE MR408i-o, for detailed descriptions reference the QuickSpecs |
| Network controller | 1 Gb, 10 Gb, 10/25 Gb, 100 Gb, or 200 Gb, in PCIe adapter or OCP 3.0 form factor, |
| Power supply | 800W, 1000W, or 1600W Dual hot-plug redundant 1+1 HPE Flexible Slot Power Supplies, depending on model |
| Remote management | HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, HPE OneView Advanced (optional, requires licenses), and HPE Compute Ops Management |
| Operating system | Windows, Linux, VMware OS support. |
| Dimensions | SFF CTO servers: 8.75 x 44.8 x 72.7. cm / 3.44 x 17.64 x 28.62 in |
| Weight | 8 SFF hard drives (no rear drives), 2x processors, 2x power supplies, 1x RAID controller, 2x Risers installed) − Maximum: 33kg/72.75 lbs. − Minimum: 16kg/35.27 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
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The HPE ProLiant DL380 Gen11 8×2.5″ Server is a next-generation, dual-socket rack server built for high-performance computing, hybrid cloud workloads, and data-intensive enterprise applications. Designed to deliver exceptional scalability and speed, it is powered by 4th and 5th Gen Intel® Xeon® Scalable Processors, supporting up to 64 cores per CPU and 8 TB DDR5 memory.
With its advanced PCIe Gen5 architecture, enhanced bandwidth, and integrated security at the silicon level, the HPE ProLiant DL380 Gen11 8×2.5″ Server is the ideal choice for organizations running mission-critical workloads, virtualization, or AI-driven applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server sets a new standard for compute performance. It supports up to two Intel Xeon Scalable processors, offering up to 64 cores per processor and 350W TDP for maximum throughput.
This server includes DDR5 Smart Memory at speeds up to 5600 MHz, delivering higher bandwidth, lower latency, and increased energy efficiency compared to DDR4. With 16 DIMM channels per processor and up to 8 TB total memory, businesses benefit from unmatched parallel processing for workloads such as virtualization, AI, ML, and data analytics.
Additionally, the support for PCIe Gen5 technology provides up to double the data transfer rate of Gen4, ensuring faster networking and higher I/O bandwidth for intensive applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server offers outstanding storage flexibility with support for multiple drive configurations. It can accommodate 8x 2.5″ SAS, SATA, or NVMe SSDs, depending on model and workload requirements.
The server’s architecture also supports hot-pluggable RAID M.2 boot options, and a range of HPE Smart Array Controllers (such as SR932i-p, MR216i-o, and MR416i-p) to ensure optimal performance, reliability, and data protection.
For businesses requiring expansion, the HPE ProLiant DL380 Gen11 8×2.5″ Server includes up to 8 PCIe Gen5 slots and 2 OCP 3.0 slots, enabling future scalability with network adapters, GPUs, or high-speed storage controllers.
Designed for high-speed communication and data throughput, the HPE ProLiant DL380 Gen11 8×2.5″ Server supports flexible networking options, including 1GbE, 10GbE, 25GbE, 100GbE, and even 200GbE adapters in PCIe or OCP 3.0 form factors.
This makes it an excellent fit for organizations that require ultra-low-latency networking, hybrid cloud environments, or large-scale data center integration. The inclusion of PCIe Gen5 lanes also enhances overall network speed and reduces bottlenecks, ensuring smoother and faster data transmission across workloads.
Security is at the heart of the HPE ProLiant DL380 Gen11 8×2.5″ Server, which integrates HPE Silicon Root of Trust—a hardware-based zero-trust architecture that ensures all firmware is authenticated before booting.
The server also leverages Intel® Software Guard Extensions (SGX) and Intel® Boot Guard, providing hardware-level protection for sensitive data and applications.
With features like TPM 2.0, intrusion detection, and secure firmware validation, the HPE ProLiant DL380 Gen11 8×2.5″ Server delivers multi-layered defense to safeguard business data from cyber threats and unauthorized access.
The HPE ProLiant DL380 Gen11 8×2.5″ Server includes HPE Integrated Lights-Out 6 (iLO 6) for advanced, secure, and remote management capabilities. IT administrators can configure, monitor, and update servers seamlessly, even from offsite locations.
For a complete cloud-based experience, HPE Compute Ops Management enables global visibility, automation, and lifecycle control of compute resources from edge to cloud.
Additionally, the server integrates with HPE OneView and HPE GreenLake, providing a unified, as-a-service management approach for hybrid infrastructure, improving operational efficiency and reducing downtime.
The HPE ProLiant DL380 Gen11 8×2.5″ Server is engineered to handle a variety of demanding workloads, including:
Virtualization and containerized environments
AI and machine learning model training
Database analytics and business intelligence
Software-defined storage (SDS)
Media processing and video transcoding
Edge and hybrid cloud infrastructure
Its scalability and performance make it a trusted platform for enterprises seeking consistent power, flexibility, and resilience in their IT environments.
The HPE ProLiant DL380 Gen11 8×2.5″ Server supports a wide array of operating systems and hypervisors, including:
Microsoft Windows Server
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
CentOS and Oracle Linux
Ubuntu Server
This broad compatibility ensures seamless integration into any enterprise ecosystem or hybrid cloud infrastructure.
Choosing the HPE ProLiant DL380 Gen11 8×2.5″ Server means choosing a future-proof solution built for performance, reliability, and scalability. It combines next-generation Intel Xeon Scalable processors, DDR5 memory, and PCIe Gen5 technology to deliver industry-leading efficiency.
With HPE’s Silicon Root of Trust, iLO 6, and Compute Ops Management, organizations benefit from enhanced automation, zero-trust security, and simplified IT operations—making it ideal for any modern data center or enterprise deployment.
In conclusion, the HPE ProLiant DL380 Gen11 8×2.5″ Server stands out as one of the most powerful and secure servers in its class. It offers advanced compute capabilities, flexible storage options, and enterprise-grade security designed for the hybrid cloud era.
Whether used for AI workloads, virtualization, or mission-critical business applications, the HPE ProLiant DL380 Gen11 8×2.5″ Server ensures exceptional reliability, intelligent management, and scalable performance—empowering organizations to meet evolving IT demands with confidence.
| Form factor | 2U |
|---|---|
| Processor | 5th Gen Intel® Xeon® Scalable Processors and 4th Gen Intel® Xeon® Scalable Processors |
| Ram type | DDR5 |
| Total Memory slots | 32 DIMM Slots |
| Max memory | 8.0 TB 32 x 256 GB RDIMM @ 4800 MT/s |
| PCIe slots | Up to 8 PCIe Gen5, and 2 OCP 3.0 |
| Support hard drive | 8 SFF SAS/SATA/SSD |
| Support raid controller | HPE SR932i-p and/or HPE MR216i-o and/or HPE MR416i-o and/or HPE MR216i-p and/or HPE MR416i-p and/or HPE MR408i-o, for detailed descriptions reference the QuickSpecs |
| Network controller | 1 Gb, 10 Gb, 10/25 Gb, 100 Gb, or 200 Gb, in PCIe adapter or OCP 3.0 form factor, |
| Power supply | 800W, 1000W, or 1600W Dual hot-plug redundant 1+1 HPE Flexible Slot Power Supplies, depending on model |
| Remote management | HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, HPE OneView Advanced (optional, requires licenses), and HPE Compute Ops Management |
| Operating system | Windows, Linux, VMware OS support. |
| Dimensions | SFF CTO servers: 8.75 x 44.8 x 72.7. cm / 3.44 x 17.64 x 28.62 in |
| Weight | 8 SFF hard drives (no rear drives), 2x processors, 2x power supplies, 1x RAID controller, 2x Risers installed) − Maximum: 33kg/72.75 lbs. − Minimum: 16kg/35.27 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
The HPE ProLiant DL380 Gen11 8×2.5″ Server is a next-generation, dual-socket rack server built for high-performance computing, hybrid cloud workloads, and data-intensive enterprise applications. Designed to deliver exceptional scalability and speed, it is powered by 4th and 5th Gen Intel® Xeon® Scalable Processors, supporting up to 64 cores per CPU and 8 TB DDR5 memory.
With its advanced PCIe Gen5 architecture, enhanced bandwidth, and integrated security at the silicon level, the HPE ProLiant DL380 Gen11 8×2.5″ Server is the ideal choice for organizations running mission-critical workloads, virtualization, or AI-driven applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server sets a new standard for compute performance. It supports up to two Intel Xeon Scalable processors, offering up to 64 cores per processor and 350W TDP for maximum throughput.
This server includes DDR5 Smart Memory at speeds up to 5600 MHz, delivering higher bandwidth, lower latency, and increased energy efficiency compared to DDR4. With 16 DIMM channels per processor and up to 8 TB total memory, businesses benefit from unmatched parallel processing for workloads such as virtualization, AI, ML, and data analytics.
Additionally, the support for PCIe Gen5 technology provides up to double the data transfer rate of Gen4, ensuring faster networking and higher I/O bandwidth for intensive applications.
The HPE ProLiant DL380 Gen11 8×2.5″ Server offers outstanding storage flexibility with support for multiple drive configurations. It can accommodate 8x 2.5″ SAS, SATA, or NVMe SSDs, depending on model and workload requirements.
The server’s architecture also supports hot-pluggable RAID M.2 boot options, and a range of HPE Smart Array Controllers (such as SR932i-p, MR216i-o, and MR416i-p) to ensure optimal performance, reliability, and data protection.
For businesses requiring expansion, the HPE ProLiant DL380 Gen11 8×2.5″ Server includes up to 8 PCIe Gen5 slots and 2 OCP 3.0 slots, enabling future scalability with network adapters, GPUs, or high-speed storage controllers.
Designed for high-speed communication and data throughput, the HPE ProLiant DL380 Gen11 8×2.5″ Server supports flexible networking options, including 1GbE, 10GbE, 25GbE, 100GbE, and even 200GbE adapters in PCIe or OCP 3.0 form factors.
This makes it an excellent fit for organizations that require ultra-low-latency networking, hybrid cloud environments, or large-scale data center integration. The inclusion of PCIe Gen5 lanes also enhances overall network speed and reduces bottlenecks, ensuring smoother and faster data transmission across workloads.
Security is at the heart of the HPE ProLiant DL380 Gen11 8×2.5″ Server, which integrates HPE Silicon Root of Trust—a hardware-based zero-trust architecture that ensures all firmware is authenticated before booting.
The server also leverages Intel® Software Guard Extensions (SGX) and Intel® Boot Guard, providing hardware-level protection for sensitive data and applications.
With features like TPM 2.0, intrusion detection, and secure firmware validation, the HPE ProLiant DL380 Gen11 8×2.5″ Server delivers multi-layered defense to safeguard business data from cyber threats and unauthorized access.
The HPE ProLiant DL380 Gen11 8×2.5″ Server includes HPE Integrated Lights-Out 6 (iLO 6) for advanced, secure, and remote management capabilities. IT administrators can configure, monitor, and update servers seamlessly, even from offsite locations.
For a complete cloud-based experience, HPE Compute Ops Management enables global visibility, automation, and lifecycle control of compute resources from edge to cloud.
Additionally, the server integrates with HPE OneView and HPE GreenLake, providing a unified, as-a-service management approach for hybrid infrastructure, improving operational efficiency and reducing downtime.
The HPE ProLiant DL380 Gen11 8×2.5″ Server is engineered to handle a variety of demanding workloads, including:
Virtualization and containerized environments
AI and machine learning model training
Database analytics and business intelligence
Software-defined storage (SDS)
Media processing and video transcoding
Edge and hybrid cloud infrastructure
Its scalability and performance make it a trusted platform for enterprises seeking consistent power, flexibility, and resilience in their IT environments.
The HPE ProLiant DL380 Gen11 8×2.5″ Server supports a wide array of operating systems and hypervisors, including:
Microsoft Windows Server
VMware vSphere / ESXi
Red Hat Enterprise Linux (RHEL)
SUSE Linux Enterprise Server (SLES)
CentOS and Oracle Linux
Ubuntu Server
This broad compatibility ensures seamless integration into any enterprise ecosystem or hybrid cloud infrastructure.
Choosing the HPE ProLiant DL380 Gen11 8×2.5″ Server means choosing a future-proof solution built for performance, reliability, and scalability. It combines next-generation Intel Xeon Scalable processors, DDR5 memory, and PCIe Gen5 technology to deliver industry-leading efficiency.
With HPE’s Silicon Root of Trust, iLO 6, and Compute Ops Management, organizations benefit from enhanced automation, zero-trust security, and simplified IT operations—making it ideal for any modern data center or enterprise deployment.
In conclusion, the HPE ProLiant DL380 Gen11 8×2.5″ Server stands out as one of the most powerful and secure servers in its class. It offers advanced compute capabilities, flexible storage options, and enterprise-grade security designed for the hybrid cloud era.
Whether used for AI workloads, virtualization, or mission-critical business applications, the HPE ProLiant DL380 Gen11 8×2.5″ Server ensures exceptional reliability, intelligent management, and scalable performance—empowering organizations to meet evolving IT demands with confidence.
| Form factor | 2U |
|---|---|
| Processor | 5th Gen Intel® Xeon® Scalable Processors and 4th Gen Intel® Xeon® Scalable Processors |
| Ram type | DDR5 |
| Total Memory slots | 32 DIMM Slots |
| Max memory | 8.0 TB 32 x 256 GB RDIMM @ 4800 MT/s |
| PCIe slots | Up to 8 PCIe Gen5, and 2 OCP 3.0 |
| Support hard drive | 8 SFF SAS/SATA/SSD |
| Support raid controller | HPE SR932i-p and/or HPE MR216i-o and/or HPE MR416i-o and/or HPE MR216i-p and/or HPE MR416i-p and/or HPE MR408i-o, for detailed descriptions reference the QuickSpecs |
| Network controller | 1 Gb, 10 Gb, 10/25 Gb, 100 Gb, or 200 Gb, in PCIe adapter or OCP 3.0 form factor, |
| Power supply | 800W, 1000W, or 1600W Dual hot-plug redundant 1+1 HPE Flexible Slot Power Supplies, depending on model |
| Remote management | HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, HPE OneView Advanced (optional, requires licenses), and HPE Compute Ops Management |
| Operating system | Windows, Linux, VMware OS support. |
| Dimensions | SFF CTO servers: 8.75 x 44.8 x 72.7. cm / 3.44 x 17.64 x 28.62 in |
| Weight | 8 SFF hard drives (no rear drives), 2x processors, 2x power supplies, 1x RAID controller, 2x Risers installed) − Maximum: 33kg/72.75 lbs. − Minimum: 16kg/35.27 lbs. |
| Operation temperature | 10°C to 35°C (50°F to 95°F) |
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